Ozone therapy is a complementary treatment that uses a carefully measured mixture of medical-grade oxygen and ozone (O₃). It is used in several European and Asian countries as part of integrative care for inflammation, circulation and recovery. This article explains how it is thought to work, how it is given, what the evidence shows, and the safety rules that matter.
How does ozone therapy work?
Ozone is a highly reactive form of oxygen. In small, controlled doses it creates a brief, mild oxidative stress. This is thought to prompt the body to switch on its own antioxidant defences, improve how red blood cells release oxygen to tissues, and modulate immune activity. The dose matters: therapeutic ozone is given in precise concentrations from a medical ozone generator.
How is ozone therapy given?
- Major autohaemotherapy (MAH): a small amount of your blood is drawn, mixed with oxygen–ozone gas, and returned through a drip.
- Rectal insufflation: a small volume of gas is introduced into the rectum, where it is absorbed.
- Local injections: ozone injected into or around joints, discs or soft tissue for pain.
- Topical ozone: ozonated oils or “bagging” used for skin and wound care.
What is ozone therapy used for?
Research on ozone therapy is still developing. The most studied areas include:
- Back pain from disc herniation and knee osteoarthritis, using local injections.
- Chronic wounds, including diabetic foot ulcers, where ozone may support healing.
- Chronic inflammation and fatigue, as part of an integrative inflammation and root-cause programme.
- Circulation and recovery support.
Ozone therapy is considered complementary. Major regulators such as the US FDA have not approved ozone for treating specific diseases, and larger high-quality trials are still needed. It works best as one part of a broader plan that also addresses diet, activity, sleep and any underlying medical conditions.
Who should not have ozone therapy?
- People with G6PD deficiency, because ozone can trigger red blood cell breakdown. G6PD testing is important in Malaysia, where the condition is relatively common.
- Pregnant women.
- People with uncontrolled hyperthyroidism, severe anaemia or bleeding disorders.
- Anyone who has had a recent heart attack or stroke, or who has uncontrolled high blood pressure.
What to expect
Your first visit includes a consultation and, where needed, blood tests. A typical MAH session takes 45–60 minutes. Most people feel well afterwards; some feel mildly tired. Courses usually involve several sessions, reviewed by your doctor as you go.
At Montis, oxygen-based therapies sit within our Detox and Defence pillars. They are always planned after medical screening.
Frequently asked questions
Is ozone therapy safe?
When performed by trained clinicians with correct dosing and screening (including G6PD testing), serious side effects are uncommon. Risks rise with incorrect doses, poor technique or inhalation, which is why it should only be done in a medical setting.
How many ozone sessions will I need?
It varies with the goal. Courses of 5 to 10 sessions are common, followed by a review. Your doctor will tailor the plan and stop if you are not benefiting.
Can ozone therapy replace my medication?
No. Ozone therapy is complementary and should not replace medicines prescribed by your doctor.
This article is for general information only and is not a substitute for personal medical advice. Treatments described may not be suitable for everyone. Please consult a qualified doctor before starting any treatment.
